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Sildenafil citrate, commonly known by the brand name, is a prescription-only medicine used to treat erectile dysfunction (ED) in adult men. It works by improving blood flow to the penis, helping to achieve and maintain an erection during sexual activity.

Dosage and Administration

Sildenafil is available in 25mg, 50mg, and 100mg strengths.

  • The usual starting dose is 50mg, taken approximately one hour before sexual activity.
  • Dosage can be adjusted depending on individual response and tolerability.
  • Take only one tablet in 24 hours, with or without food.
  • Avoid grapefruit juice, as it can increase the risk of side effects.
  • A high-fat meal may delay onset of action.

Effectiveness

Sildenafil has been shown to be effective in up to 80% of men with ED, with effects typically noticeable within 30 to 60 minutes, and lasting for up to 4–5 hours.

Side Effects

Common side effects include:

  • Headache
  • Flushing
  • Nasal congestion
  • Indigestion

Less common but serious effects include visual disturbances, hearing changes, or prolonged erections. Seek medical attention if severe or persistent side effects occur.

Contraindications

Sildenafil should not be used by those:

  • Taking nitrates for chest pain
  • With severe heart or liver conditions
  • Under 18 years of age
  • With certain medication interactions (e.g. alpha-blockers, antifungals, antibiotics)

Interactions

Inform your doctor of all medications and supplements before use. Interactions may occur with:

  • Nitrates
  • Alpha-blockers
  • Some antibiotics and antifungal medicines

Alcohol and Heart Conditions

Avoid excessive alcohol while taking sildenafil, as it can lower blood pressure and increase side effect risk. Use with caution if you have any heart-related conditions.

Availability and Cost

Sildenafil is available by prescription only in the UK.

  • Generic versions are more affordable than branded Viagra.
  • Supplied by licensed UK pharmacies such as Online Chemist.
  • Avoid counterfeit products from unregulated websites.

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Sildenafil (Viagra) is a popular medication used to treat erectile dysfunction (ED) in men. It works by increasing blood flow to the penis, helping to achieve and maintain an erection during sexual activity. In addition, it helps to improve blood flow to the penis, which can benefit men who are sensitive to sexual performance issues.

Sildenafil Connect works by allowing blood vessels in the penis to relax, allowing more blood to flow into the penis. This, in turn, helps men with ED to achieve and maintain an erection.

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Viagra Connect contains Sildenafil Citrate, the same active ingredient as Viagra, and is used to treat erectile dysfunction (ED) in men. It lowers blood pressure and improves blood flow, which can help men with ED to achieve and maintain an erection.

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This product is a Prescription Only Medicine (S4) and is sold by Healthylife Pharmacy, an independently owned and operated pharmacy business. This prescription product requires a valid Australian script.

Healthylife provides general product information such as nutritional information, country of origin and product packaging for your convenience. This information is intended as a guide only, including because products change from time to time. Please read product labels before consuming. For therapeutic goods, always read the label and follow the directions for use on pack. If you require specific information to assist with your purchasing decision, we recommend that you contact the manufacturer via the contact details on the packaging or email us at [email protected]. Product ratings and reviews are taken from various sources including Bazaarvoice. Healthylife does not represent or warrant the accuracy of any statements, claims or opinions made in product ratings and reviews.

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Healthylife contains an active ingredient, which is classED on the market, which is a prescription only medication. This product is a prescription only medication, and therefore only the brand names, manufacturers, quantities and strengths you are advised are indicated. You must have a valid Australian script to buy this product.

Healthylife contains an active ingredient, which is a prescription only medication. This product is a prescription only medication, and therefore only the brand names, manufacturers, quantities and strengths you are advising are indicated.

A new study suggests that men who use the drug Viagra will likely have erectile dysfunction. But, researchers at the University of Southampton found that a new drug to improve erectile function might also help men who use it too much.

Viagra, sold under the brand name Sildenafil, and the medicine sildenafil citrate are the main ingredients in Viagra. The researchers looked at a group of men who took Viagra on a daily basis. They compared the effects of the two drugs on two key variables:

They found that men who used Viagra daily had higher rates of erectile dysfunction. However, there was no evidence that taking Viagra was related to this.

“It’s just interesting that this is the first time we have seen an increase in the severity of erectile dysfunction in men who take Viagra daily. We can’t confirm that the medication did this, but that it did in fact have an effect on men who have erectile dysfunction,” said Dr. Paul G. Tumic, chairman of urology at the Southampton NHS Foundation Trust.

Dr. Tumic said: “It’s an interesting finding, but we’ve seen so many cases of ED since the last time we have looked at this topic, particularly in young men, and there’s still so much we don’t know about how well it interacts with other medications.

“There are a number of reasons why we need to explore other treatments for ED, including psychological therapy, lifestyle changes, and improving overall health.”

Viagra is to treat erectile dysfunction. (Photo: AP)

(Photo: Getty Images)Credit: Getty Images/iStockphoto

Viagra is a medication that belongs to the class of drugs known as phosphodiesterase-5 (PDE5) inhibitors. It is used to treat erectile dysfunction in men. (Photo: Getty Images/iStockphoto)

The study, published in the journal, “Erectile Function, Impotence and Sexual Health: A Systematic Review of the Evidence,” looked at 50,000 men from the Southampton Health Alliance from 1998 to 2002.

Introduction to Sildenafil

Sildenafil, a phosphodiesterase type 5 inhibitor, is widely used as an effective treatment for erectile dysfunction (ED) and pulmonary arterial hypertension (PAH). Its effectiveness in improving erectile function has made it a cornerstone in various therapeutic areas.

Market Size and Growth

The global sildenafil market is segmented of Sildenafil in the market from “Low” to “High”. The low- to medium-impact market was valued at USD 4.45 billion in 2023 and is projected to reach USD 5.87 billion by 2031, growing at a Compound Annual Growth Rate (CAGR) of 4.5% from 2024 to 2031[1].

Current Market Segments and Expert Repertory

The market includes sildenafil- target patients, pharmaceutical industry professionals, academic research institutions, and medical andcientious Industries (MIPEs) like tailors and distributors.

  • North America: This region is significant from the present day, with 15 million patients suffering from ED, considered the third most common condition world-wide, with $80.6 billion in 2022. The market in North America is driven by the high prevalence of ED and the presence of healthcare professionals and private insurers[1].
  • Asia Pacific: This region is also a significant player in the global market with 40% market share in countries like China, Japan, South Korea, and India. The market in Asia Pacific is driven by the rising incidence of hypertension and obesity, driven by improved quality of life and reduced mortality[1].
  • Europe: Europe is the fastest-growing region in product quality and healthcare expenditure. Asia Pacific is expected to the top from 2017 as the region experiences significant growth[1].

Regional Analysis

The market growth in Asia Pacific is driven by countries like India, China, and Japan, which are becoming global competitors for pharmaceuticals, biocides, and natural resources. The Asia Pacific region is expected to be the fastest-growing from a market size of USD 40.9 billion in 2023[1].

Drivers

The rising incidence of diabetes and cardiovascular diseases, particularly in diabetes management, has been a major driver of the market. A recent study by the National Library of Medicine (SLOG) revealed that the prevalence of ED was approximately 26% in patients with diabetes[2].

How It Works

Sildenafil, the active ingredient in Viagra, works by inhibiting phosphodiesterase type 5 (PDE5) in the walls of erecting cells. This prevents blood flow into the penis, allowing for an erection to occur. Sildenafil’s effects last from four to six hours, with an onset time of approximately five to six hours. This mechanism of action makes it effective for improving erectile function[3].

Pulmonary Arterial Hypertension

Pulmonary arterial hypertension (PAH) is a medical condition in which smooth muscle in the pulmonary arteries, known as the myocardium, becomes enlarged, causing heart failure. Sildenafil, the active ingredient, works by relaxing these blood vessels and widening them, leading to blood flow restriction and eventually left-sided heart failure[1][4].

Market Segments

Market Share

By Application

Erectile dysfunction (ED), characterized by difficulties with achieving or maintaining an erection, has become a top-seller. Sildenafil, marketed under the brand name Viagra, is a treatment product for many common symptoms of ED. Here are some key drivers to keep an eye on:

Pricing and Pricing Details

The pricing of sildenafil varies depending on the dosage form and dosage. The generic version, sildenafil citrate, is typically more affordable. However, the pricing varies depending on location and timing. The prices can be found in the manufacturer’s patient information leaflets or in the pharmacy’s price. Also, the prices can be found in the pharmacy’s price. The sildenafil price varies depending on the form and dosage. The generic form, sildenafil citrate, is usually more affordable[1].

Note: Other medications can affect how Sildenafil is processed in your body, potentially impacting its effectiveness. These include azole antifungals (such as itraconazole or ketoconazole), macrolide antibiotics (such as clarithromycin or erythromycin), HIV protease inhibitors (such as saquinavir), mifepristone, rifampin, and ritonavir.

Combining Sildenafil with other medications for erectile dysfunction (ED) or pulmonary hypertension, such as tadalafil or vardenafil, is harmful.

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Consider these products with in-clinic medications that are ED or PH blockers:

  • Herbal supplements like Tums or Gokhayash.
  • Other PDE5 inhibitors.

Learn more

Dosage Information:This drug information does not cover all possible uses and side effects of Sildenafil.

Adults

  • Add one 50 mg tablet per day.
  • Add one 100 mg tablet per day.

Acts most often found using Sildenafil in pulmonary hypertension drugs, but it may interact with other medications. Check with your doctor before using any other medications for PH.

Children

  • Add one 100 mg tablet per kg.

Acts most often found using Sildenafil in anovulatory infertility drugs, but it may interact with other medications.

Elderly

  • Use inlude or undefined method methods

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Considerations

Before taking Sildenafil it is important to tell your doctor if you have any medical conditions, especially the following:

  • Allergies to the ingredients?
  • Liver disease
  • Allergies to the preservatives or inhibitors of the liver (such as caffeine, lithium)

Side Effects

In some cases, Sildenafil can cause side effects. Watch for these rare reactions:

  • Dizziness
  • Headache
  • Indigestion
  • Heartburn
  • Stuffy nose

Cost

The cost of Sildenafil can vary depending on factors like the dosage, quantity, and whether it's purchased in bulk or under},{"ixty-eight cents]

Quick information

For PDE5 inhibitors:

  • Take 1 tablet about 1 hour before intercourse.
  • It's best to take Sildenafil about an hour before intercourse.
  • Avoid Sildenafil with nitrates, as it can cause a high blood pressure that may be dangerous.